Human Recombinant Fractalkine (from E. coli)Supplier: PeproTech
300-31-1MG 300-31-100UG 300-31-500UG 300-31-5UG 300-31-20UG 300-31-250UG 300-31-50UG
10773-816EA 5644.82 CAD10773-816 10773-810 10773-814 10773-804 10773-806 10773-812 10773-808
Human Recombinant Fractalkine (from E. coli)
Proteins and Peptides
Fractalkine is a CX3CL chemokine that signals through the CX3CR1 receptor. Fractalkine has been shown to chemoattract monocytes, microglia cells and NK cells. Fractalkine is, at this time, the only CXC3C chemokine that contains three amino acid residues between the first and second cysteine residues of the chemokine domain. The Fractalkine gene encodes for a 397 amino acid precursor protein containing a 24 amino acid signal sequence, a chemokine domain, and a "mucin-like stalk" sequence, which is followed by the transmembrane domain containing approximately 20 amino acids, and a C-terminal cytoplasmic domain. The extracellular chemokine domain contains 76 amino acid residues, including the four conserved cysteine residues found in other chemokines. Recombinant Human Fractalkine (CX3CL1) is an 8.5 kDa protein containing 76 amino acid residues, including the four conserved cysteine residues present in CC chemokines.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.