Human Recombinant BD-5 (from E. coli)Supplier: PeproTech
300-68-500UG 300-68-20UG 300-68-100UG 300-68-1MG 300-68-250UG 300-68-5UG
10774-138EA 3459.03 CAD10774-138 10774-132 10774-134 10774-140 10774-136 10774-130
Human Recombinant BD-5 (from E. coli)
Proteins and Peptides
Defensins (α and β) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant Human BD-5 is a 5.8 kDa protein containing 51 amino acid residues.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.