Human Recombinant 4-1BB (from E. coli)Supplier: PeproTech
310-15-250UG 310-15-500UG 310-15-100UG 310-15-1MG 310-15-20UG 310-15-5UG
10774-252EA 1970.75 CAD10774-252 10774-254 10774-250 10774-256 10774-248 10774-246
Human Recombinant 4-1BB (from E. coli)
Proteins and Peptides
4-1BB receptor, a member of the TNFR superfamily of receptors, is mainly expressed on the surface of T cells, but also found in B cells, monocytes, and various transformed cell lines. 4-1BB receptor binds to 4-1BBL to provide a co-stimulatory signal for T lymphocytes. Signaling by 4-1BB receptor has been implicated in the antigen-presentation process and generation of cytotoxic T cells. The human 4-1BB receptor gene codes for a 255 amino acid type I transmembrane protein containing a 17 amino acid N-terminal signal sequence, a 169 amino acid extracellular domain, a 27 amino acid transmembrane domain and a 42 amino acid cytoplasmic domain. Recombinant Human 4-1BB Receptor is a 167 amino acid polypeptide (17.7 kDa), which contains the cysteine-rich TNFR-like extracellular domain of 4-1BB receptor.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.