Human Recombinant TACI (from E. coli)Supplier: PeproTech
310-17-20UG 310-17-500UG 310-17-100UG 310-17-1MG 310-17-5UG 310-17-250UG
10774-272EA 366.09 CAD10774-272 10774-278 10774-274 10774-280 10774-270 10774-276
Human Recombinant TACI (from E. coli)
Proteins and Peptides
TACI, a member of the TNF Receptor superfamily, is expressed in the small intestine, spleen, thymus, peripheral blood leukocytes, activated T cells, and resting B cells. TACI can bind to both APRIL and BAFF, stimulate the activation of transcription factors NF-κB and AP-1, and can mediate the calcineurin-dependent activation of NF-AT (nuclear-factor of activated T cells). TACI also plays a key role in the stimulation of B and T cell function. Soluble TACI inhibits APRIL-stimulated proliferation of primary B cells by blocking the binding of APRIL to the membrane-anchored TACI receptor. Recombinant Human TACI is a soluble 159 amino acid polypeptide (17.8 kDa) comprising the TNFR homologous, cysteine-rich extracellular domain of the TACI protein.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.