Rat Recombinant IL-13 (from E. coli)Supplier: PeproTech
400-16-2UG 400-16-100UG 400-16-250UG 400-16-10UG 400-16-500UG 400-16-1MG
10774-500EA 150.18 CAD10774-500 10774-504 10774-506 10774-502 10774-508 10774-510
Rat Recombinant IL-13 (from E. coli)
Proteins and Peptides
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching, resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 are cross-species reactive. Recombinant Rat IL-13 is an 11.9 kDa protein consisting of 109 amino acid residues.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.