Rat Recombinant SCF (from E. coli)

Supplier: PeproTech

400-22-1MG 400-22-250UG 400-22-10UG 400-22-2UG 400-22-500UG 400-22-100UG
10774-574EA 5630.72 CAD
10774-574 10774-570 10774-566 10774-564 10774-572 10774-568
Rat Recombinant SCF (from E. coli)
Proteins and Peptides
SCF is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. The human SCF gene encodes for a 273 amino acid transmembrane protein, which contains a 25 amino acid N-terminal signal sequence, a 189 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 36 amino acid cytoplasmic domain. The secreted soluble form of SCF is generated by proteolytic processing of the membrane anchored precursor. Recombinant Rat SCF is an 18.4 kDa polypeptide containing 165 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
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