Human Recombinant IGFBP3 (from E. coli)Supplier: PeproTech
AF10008500UG AF10008250UG AF100081MG AF10008100UG AF100085UG AF1000825UG
10777-978EA 3806.03 CAD10777-978 10777-976 10777-980 10777-974 10777-970 10777-972
Human Recombinant IGFBP3 (from E. coli)
Proteins and Peptides
IGF-BP3 is a 30 kDa, cysteine-rich secreted protein. It is the major IGF binding protein present in the plasma of human and animals, and it is also found in ?-granules of platelets. In addition to its ability to modulate the activity of IGF-I and IGF-II, IGF-BP3 exerts inhibitory effects on follicle stimulating hormone (FSH) activity. Decreased plasma levels of IGF-BP3 often results in dwarfism, whereas elevated levels of IGF-BP3 may lead to acromegaly. The expression of IGF-BP3 in fibroblasts is stimulated by mitogenic growth factors, such as Bombesin, Vasopressin, PDGF, and EGF. Recombinant Human IGF-BP3 is a 28.8 kDa protein consisting of 264 amino acid residues.Manufactured using all Animal-Free reagents.
- Carrier free
GASSGGLGPV VRCEPCDARA LAQCAPPPAV CAELVREPGC GCCLTCALSE GQPCGIYTER CGSGLRCQPS PDEARPLQAL LDGRGLCVNA SAVSRLRAYL LPAPPAPGNA SESEEDRSAG EVESPSVSST HRVSDPKFHP LHSKIIIIKK GHAKDSQRYK VDYESQSTDT QNFSSESKRE TEYGPCRREM EDTLNHLKFL NVLSPRGVHI PNCDKKGFYK KKQCRPSKGR KRGFCWCVDK YGQPLPGYTT KGKEDVHCYS MQSK
Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.