Human Recombinant TGF-beta3 (from E. coli)Supplier: PeproTech
AF10036E2UG AF10036E250UG AF10036E10UG AF10036E500UG AF10036E1MG AF10036E100UG
10778-108EA 182.81 CAD10778-108 10778-114 10778-110 10778-116 10778-118 10778-112
Human Recombinant TGF-beta3 (from E. coli)
Proteins and Peptides
The three mammalian isoforms of TGF-β, TGF-β1, β2, and β3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility, as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes, including embryogenesis, tissue remodeling and wound healing. They are secreted predominantly as latent complexes, which are stored at the cell surface and in the extracellular matrix. The release of the biologically active TGF-β isoform from a latent complex involves proteolytic processing of the complex and/or induction of conformational changes by proteins such as thrombospondin-1. The physiological role of TGF-β3 is still unknown, but its expression pattern suggests a role in the regulation of certain development processes. Recombinant Human TGF-β3 is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.