Human;Mouse;Rat Recombinant Activin (from E. coli)Supplier: PeproTech
AF12014E10UG AF12014E250UG AF12014E50UG AF12014E2UG AF12014E500UG AF12014E100UG AF12014E1MG
10778-174EA 413.72 CAD10778-174 10778-180 10778-176 10778-172 10778-182 10778-178 10778-184
Human;Mouse;Rat Recombinant Activin (from E. coli)
Proteins and Peptides
Activin A is a TGF-β family member that exhibits a wide range of biological activities, including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Activin A binds to the two forms of activin receptor type I (Act RI-A and Act RI-B) and two forms of activin receptor type II (Act RII-A and Act RII-B). Activins are homodimers or heterodimers of different β subunits. They are produced as precursor proteins with an amino terminal propeptide that is cleaved to release the C-terminal bioactive ligand. Recombinant Human/Murine/Rat Activin A is a 26.0 kDa disulfide-linked homodimer of two βA chains, each containing 116 amino acid residues.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.