Human Recombinant GDF-3 (from E. coli)Supplier: PeproTech
AF12022500UG AF12022100UG AF1202220UG AF120221MG AF12022250UG AF120225UG
10778-194EA 4842.39 CAD10778-194 10778-190 10778-188 10778-196 10778-192 10778-186
Human Recombinant GDF-3 (from E. coli)
Proteins and Peptides
GDF-3 is a member of the TGF-β superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF-β family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia that characterizes Type 2 diabetes. Recombinant Human GDF-3 is a 26.0 kDa non-disulfide-linked homodimer containing two 114 amino acid polypeptide chains.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.