Human Recombinant LIF (from E. coli)Supplier: PeproTech
AF300055UG AF3000525UG AF30005500UG AF30005250UG AF30005100UG AF300051MG
10778-588EA 187.38 CAD10778-588 10778-590 10778-596 10778-594 10778-592 10778-598
Human Recombinant LIF (from E. coli)
Proteins and Peptides
LIF is a pleiotrophic factor produced by multiple cell types, including T cells, myelomonocytic lineages, fibroblasts, liver, heart and melanoma. LIF promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Other activities include the stimulation of acute phase protein synthesis by hepatocytes, stimulation of differentiation of cholinergic nerves, and suppression of adipogenesis by inhibiting the lipoprotein lipase in adipocytes. While human LIF is active on mouse cells and is widely used in the maintenance of murine ESC to prevent spontaneous differentiation, mouse LIF is not active on human cells due to its inability to bind to the human LIF receptor. Recombinant Human LIF is a 19.6 kDa protein containing 180 amino acids residues, including three disulfide bonds. Manufactured using all Animal-Free reagents.
- Carrier free
SPLPITPVNA TCAIRHPCHN NLMNQIRSQL AQLNGSANAL FILYYTAQGE PFPNNLDKLC GPNVTDFPPF HANGTEKAKL VELYRIVVYL GTSLGNITRD QKILNPSALS LHSKLNATAD ILRGLLSNVL CRLCSKYHVG HVDVTYGPDT SGKDVFQKKK LGCQLLGKYK QIIAVLAQAF
Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.