Human Recombinant BD-5 (from E. coli)

Supplier: PeproTech

AF300685UG AF300681MG AF30068250UG AF30068500UG AF30068100UG AF3006820UG
10778-724EA 182.81 CAD
10778-724 10778-734 10778-730 10778-732 10778-728 10778-726
Human Recombinant BD-5 (from E. coli)
Proteins and Peptides
  • Animal-free

Defensins (α and β) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant Human BD-5 is a 5.8 kDa protein containing 51 amino acid residues.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
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