Human;Mouse;Rat Recombinant BMP-2 (from CHO cells)Supplier: PeproTech
120-02C-500UG 120-02C-1MG 120-02C-10UG 120-02C-100UG 120-02C-250UG 120-02C-2UG
10779-106EA 5997.38 CAD10779-106 10779-108 10779-100 10779-102 10779-104 10779-098
Human;Mouse;Rat Recombinant BMP-2 (from CHO cells)
Proteins and Peptides
BMPs (Bone Morphogenetic Proteins) belong to the TGF-β superfamily of structurally related signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with an osteoconductive carrier such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 appears to play an important role in cardiac morphogenesis, and is expressed in a variety of other tissues, including lung, liver, spleen, prostate, ovary, and small intestine. The functional form of BMP-2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains (monomers) linked by a single disulfide bond. Each BMP-2 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 23 amino acid signal sequence for secretion, and a 259 amino acid propeptide. After dimerization of this precursor, the covalent bonds between the propeptide (which is also a disulfide-linked homodimer) and the mature BMP-2 ligand are cleaved by a furin-type protease. Recombinant Human/Murine/Rat BMP-2 derived from
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.