Human Recombinant PAF-AH (from HEK293 cells)Supplier: PeproTech
140-10-20UG 140-10-250UG 140-10-5UG 140-10-100UG 140-10-1MG 140-10-500UG
10779-434EA 366.09 CAD10779-434 10779-438 10779-432 10779-436 10779-442 10779-440
Human Recombinant PAF-AH (from HEK293 cells)
Proteins and Peptides
Platelet Activating Factor (PAF) is a biologically active phospholipid, which exerts primarily proinflammatory activities by specifically signaling through G-protein-coupled receptors on platelets, neutrophils, and monocytes. Platelet Activating Factor Acetylhydrolase (PAF-AH) is a secreted protein that mediates PAF activity by specifically catalyzing hydrolysis of the “sn2” ester bond, resulting in the conversion of PAF to the biologically inactive lyso-PAF. PAF-AH can also interact with LDL particles to induce the hydrolysis of LDL-associated, oxidized phospholipids, generating lysophosphatidylcholine (lyso-PC) and other lysophospholipids. Recombinant Human PAF-AH is a 420 amino acid glycoprotein which migrates with an apparent molecular mass of 47-55 kDa by SDS-PAGE analysis. Recombinan Human PAF-AH has a calculated, theoretical meolecular weight of 47.8 kDa.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.