Human Recombinant PECAM-1 (from HEK293 cells)Supplier: PeproTech
150-06-50UG 150-06-500UG 150-06-10UG 150-06-1MG 150-06-250UG 150-06-100UG
10779-502EA 366.09 CAD10779-502 10779-508 10779-500 10779-510 10779-506 10779-504
Human Recombinant PECAM-1 (from HEK293 cells)
Proteins and Peptides
PECAM is transmembrane glycoprotein that belongs to the Ig-related superfamily of adhesion molecules. It is highly expressed at endothelial cell junctions, and is also expressed in platelets and most leukocyte sub-types. The primary function of PECAM-1 is the mediation of leukocyte-endothelial cell adhesion and signal transduction. PECAM-1 has been implicated in the pathogenesis of various inflammation-related disorders, including thrombosis, multiple sclerosis (MS), and rheumatoid arthritis. The human PECAM-1 gene codes for a 738 amino acid transmembrane glycoprotein that contains a 118 amino acid cytoplasmic domain, a 19 amino acid transmembrane domain, and a 574 amino acid extracellular domain. Recombinant Human PECAM-1 is a 572 amino acid glycoprotein comprising the extracellular domain of PECAM-1. Monomeric glycosylated PECAM-1 migrates at an apparent molecular weight of approximately 80.0-95.0 kDa by SDS-PAGE analysis under reducing conditions. The calculated molecular weight of Recombinan Human PECAM-1 is 64.3 kDa.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.