Mouse Recombinant MIP-1alpha (from E. coli)Supplier: PeproTech
250-09-500UG 250-09-50UG 250-09-10UG 250-09-1MG 250-09-250UG 250-09-2UG 250-09-100UG
10780-264EA 3378.39 CAD10780-264 10780-258 10780-256 10780-266 10780-262 10780-254 10780-260
Mouse Recombinant MIP-1alpha (from E. coli)
Proteins and Peptides
Both MIP-1α and MIP-1β are structurally and functionally related CC chemokines. They participate in host response to invading bacterial, viral, parasite and fungal pathogens, by regulating the trafficking, and activation state, of selected subgroups of inflammatory cells (e.g. macrophages, lymphocytes and NK cells). While both MIP-1α and MIP-1β exert similar effects on monocytes, their effect on lymphocytes differ; with MIP-1α selectively attracting CD8+ lymphocytes, and MIP-1β selectively attracting CD4+ lymphocytes. Additionally, MIP-1α and MIP-1β have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1α and MIP-1β are active on human and murine hematopoietic cells. Recombinant Murine MIP-1α (CCL3) is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.