Mouse Recombinant MIP-1beta (from E. coli)

Supplier: PeproTech

250-32-10UG 250-32-500UG 250-32-50UG 250-32-1MG 250-32-2UG 250-32-250UG 250-32-100UG
10780-352EA 366.09 CAD
10780-352 10780-360 10780-354 10780-362 10780-350 10780-358 10780-356
Mouse Recombinant MIP-1beta (from E. coli)
Proteins and Peptides
Both MIP-1α and MIP-1β are structurally and functionally related CC chemokines. They participate in host response to invading bacterial, viral, parasite and fungal pathogens, by regulating the trafficking, and activation state, of selected subgroups of inflammatory cells (.g. macrophages, lymphocytes and NK cells). While both MIP-1α and MIP-1β exert similar effects on monocytes, their effect on lymphocytes differ; with MIP-1α selectively attracting CD8+ lymphocytes, and MIP-1β selectively attracting CD4+ lymphocytes. Additionally, MIP-1α and MIP-1β have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1α and MIP-1β are active on human and murine hematopoietic cells. Recombinant Murine MIP-1β (CCL4) is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
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