Human Recombinant SCF (from E. coli)

Supplier: PeproTech

300-07-100UG 300-07-1MG 300-07-250UG 300-07-2UG 300-07-10UG 300-07-500UG 300-07-50UG
10780-454EA 925.94 CAD
10780-454 10780-460 10780-456 10780-448 10780-450 10780-458 10780-452
Human Recombinant SCF (from E. coli)
Proteins and Peptides
SCF is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. The human SCF gene encodes for a 273 amino acid transmembrane protein, which contains a 25 amino acid N-terminal signal sequence, a 189 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 36 amino acid cytoplasmic domain. The secreted soluble form of SCF is generated by proteolytic processing of the membrane anchored precursor. Recombinant Human SCF is an 18.4 kDa polypeptide containing 165 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
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