Rat Recombinant Oncostatin (from E. coli)Supplier: PeproTech
400-36-10UG 400-36-500UG 400-36-100UG 400-36-1MG 400-36-2UG 400-36-250UG
10781-042EA 366.09 CAD10781-042 10781-048 10781-044 10781-050 10781-040 10781-046
Rat Recombinant Oncostatin (from E. coli)
Proteins and Peptides
Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi’s sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi’s sarcoma cells, but inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptors in hepatoma cells. OSM shares several structural and functional characteristics with LIF, IL-6, and CNTF. Recombinant Rat Oncostatin M is a 24.4 kDa protein, containing 215 amino acid residues.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.