Human Recombinant MMP-3 (from E. coli)

Supplier: PeproTech

420-03-10UG 420-03-100UG 420-03-500UG 420-03-2UG 420-03-1MG 420-03-250UG
10781-132EA 366.09 CAD
10781-132 10781-134 10781-138 10781-130 10781-140 10781-136
Human Recombinant MMP-3 (from E. coli)
Proteins and Peptides
Matrix metalloproteinases (MMPs) are a family of endoproteases that require zinc and calcium for expressing catalytic activity. These enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. MMP-3 degrades fibronectin, laminin, collagens III, IV, and X, and cartilage proteoglycans. Recombinant Human MMP-3 is a 42.8 kDa protein containing the entire catalytic N-terminal domain and the C-terminal domain (378 amino acids).

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
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