Human Recombinant CDNF (from E. coli)Supplier: PeproTech
450-05-1MG 450-05-500UG 450-05-100UG 450-05-5UG 450-05-25UG 450-05-250UG
10781-204EA 5630.72 CAD10781-204 10781-202 10781-198 10781-194 10781-196 10781-200
Human Recombinant CDNF (from E. coli)
Proteins and Peptides
CDNF is a secreted neurotrophic factor that is expressed in brain, neuronal and certain non-neuronal tissues. It has been shown to promote survival, growth and function of dopamine-specific neurons. CDNF and its structural homolog, MANF, each contain an N-terminal saposin-like lipid binding domain, and a carboxyl-terminal domain, which is not homologous to previously characterized protein structures. CDNF and MANF can prevent 6-OHDA-induced degeneration of dopaminergic neurons by triggering survival pathways in a rat experimental model of Parkinson’s disease. Recombinant Human CDNF is an 18.5 kDa protein consisting of 162 amino acids, including 8 cysteine residues.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.