Toxin Gatx1 Trifluoroacetate, BachemSupplier: BACHEM AMERICAS INC
H-6678.0100BAEA 469.38 CADH-6678.0100BA
Toxin Gatx1 Trifluoroacetate, Bachem
Proteins and Peptides
GaTx1 is a component of the venom of the yellow scorpion (Leiurus quinquestriatus hebraeus). The highly bridged 34-peptide, a chloride channel ligand, potently and reversibly inhibits cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels when the channels are in the interburst closed state. Since the toxin inhibits CFTR only when applied to the cytoplasmic side, it is unlikely that CFTR represents the native target. Manufactured and sold under license from Georgia Tech Research Corporation, USA; patent WO/2007/137163 (PCT/US2007/069243).