Anti-S6K1 Rabbit Monoclonal Antibody [clone: B12H16L8]

Supplier: Pierce Biotechnology
CAPI701083EA 784.97 CAD
Anti-S6K1 Rabbit Monoclonal Antibody [clone: B12H16L8]
ABfinity™ recombinant antibodies are rabbit monoclonal antibodies, unmatched for producing superior results. ABfinity™ antibodies are developed by immunizing animals, screening for functionality, cloning the immunogen-specific antibody genes into high-level mammalian expression vectors, produced on a large scale, and purified with Protein A. ABfinity™ monoclonal antibodies resemble rabbit monoclonals isolated from serum or produced by hybridomas, but demonstrate greater specificity and sensitivity. Because ABfinity™ recombinant antibodies are derived from cloned DNA sequences of the heavy and light antibody chains, they are not susceptible to cell-line drift or lot-to-lot variation, thus allowing for peak specificity and performance. Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain. p70 Ribosomal Protein S6 Kinase (p70S6K) is a 70 kDa member of the ribosomal S6 kinase (RSK) family of serine/threonine kinases. It is predominantly localized in the cytoplasm, and is essential in growth factors regulated cell proliferation, pathways involving cell motility, such as metastases, the immune response, and tissue repair. p70S6K acts downstream of phosphoinositide (PI) 3-kinase, and its main physiological target is the S6 ribosomal protein, which is involved in upregulation of protein synthesis.

Recommended Dilutions: Western Blot: 1:500-1:5000, Flow Cytometry: 1:100-1:500, ChIP assay: 1 ?l

Type: Primary
Antigen: S6K1
Clonality: Monoclonal
Clone: B12H16L8
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Rat
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