Anti-IL9 Rabbit Polyclonal Antibody [clone: 2HCLC]

Supplier: Pierce Biotechnology
710253
CAPI710253EA 1546.67 CAD
CAPI710253
Anti-IL9 Rabbit Polyclonal Antibody [clone: 2HCLC]
This antibody is predicted to react with chimpanzee and non-human primate based on sequence homology. ABfinity™ recombinant antibodies are rabbit monoclonal antibodies, unmatched for producing superior results. ABfinity™ antibodies are developed by immunizing animals, screening for functionality, cloning the immunogen-specific antibody genes into high-level mammalian expression vectors, produced on a large scale and purified with Protein A. ABfinity™ oligoclonal antibodies comprise a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds—the sensitivity of a polyclonal antibody with the specificity of a monoclonal, all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody—recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets when compared with monoclonal antibodies—an oligoclonal antibody has a known mixture of light and heavy chains. This exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain. Interleukin 9 (IL9) is a cytokine that regulates a variety of hematopoietic cells. It is secreted by T-cells, and supports IL-2 independent, and IL-4 independent growth of helper T-cells. It is also a positive regulator of cell proliferation, and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates signal transducer and activator (STAT) proteins and results in IRS1 and IRS2/PI3K and MEK/ERK signaling cascades.

Recommended Dilutions: Western Blot: 1-2 ?g/ml

Type: Primary
Antigen: IL9
Clonality: Polyclonal
Clone: 2HCLC
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human
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