Anti-POLG Rabbit Polyclonal Antibody

PA535163 PA535163
CAPIPA535163EA 885.75 CAD
CAPIPA535163 10157-838
Anti-POLG Rabbit Polyclonal Antibody
This antibody is predicted to react with rat based on sequence homology. Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene.

Recommended Dilutions: Western Blot: 1:1000, Immunofluorescence: 1:10-1:50, Immunocytochemistry: 1:10-1:50, Immunohistochemistry (Paraffin): 1:10-1:50, Flow Cytometry: 1:10-1:50

Type: Primary
Antigen: POLG
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse
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