Anti-PRKAG3 Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology
PA535182
CAPIPA535182EA 1960.37 CAD
CAPIPA535182
Anti-PRKAG3 Rabbit Polyclonal Antibody
This antibody is predicted to react with bovine and mouse based on sequence homology. The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.

Recommended Dilutions: Western Blot: 1:1000

Type: Primary
Antigen: PRKAG3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human
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