Anti-TICAM1 Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology
PA535284
CAPIPA535284EA 1857.5 CAD
CAPIPA535284
Anti-TICAM1 Rabbit Polyclonal Antibody
Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.

Recommended Dilutions: Western Blot: 1:1000

Type: Primary
Antigen: TICAM1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse
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