Anti-SSEA4 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: MC-813-70]

Supplier: Pierce Biotechnology

MA1021PE
CAPIMA1021PEEA 1711.64 CAD
CAPIMA1021PE
Anti-SSEA4 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: MC-813-70]
Antibodies
It has been successfully used in ICC/IF and flow cytometry applications on human samples. Stage-specific embryonic antigen 4 (SSEA-4) is a cell surface antigen, expressed along with SSEA-3, TRA-1-60 and TRA-1-81 in embryonic stem cells, embryonal carcinoma cells and induced pluripotent stem cells (iPS). In human cells, these surface markers are down-regulated during the differentiation process, while SSEA-1 is absent in undifferentiated human stem cells and upregulated on the cell surface after retinoic acid mediated differentiation. Conversely, in mouse stem cells, SSEA-1 expression decreases with differentiation while SSEA-3 and SSEA-4 expression increase.

This Antibody has been successfully used in ICC/IF and flow cytometry applications on human samples. Stage-specific embryonic antigen 4 (SSEA-4) is a cell surface antigen, expressed along with SSEA-3, TRA-1-60 and TRA-1-81 in embryonic stem cells, embryonal carcinoma cells and induced pluripotent stem cells (iPS). In human cells, these surface markers are down-regulated during the differentiation process, while SSEA-1 is absent in undifferentiated human stem cells and upregulated on the cell surface after retinoic acid mediated differentiation. Conversely, in mouse stem cells, SSEA-1 expression decreases with differentiation while SSEA-3 and SSEA-4 expression increase.

Type: Primary
Antigen: SSEA4
Clonality: Monoclonal
Clone: MC-813-70
Conjugation: PE (Phycoerythrin)
Epitope:
Host: Mouse
Isotype: IgG3
Reactivity: Human
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