Anti-SNURF Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology
PA512422
CAPIPA5-12422EA 2561.45 CAD
CAPIPA5-12422
Anti-SNURF Rabbit Polyclonal Antibody
This antibody is predicted to react with bovine, mouse and rabbit based on sequence homology. SNURF is a highly basic protein localized to the nucleus. The evolutionarily constrained open reading frame of its gene is found on a bicistronic transcript which has a downstream ORF encoding the small nuclear ribonucleoprotein polypeptide N. The upstream coding region utilizes the first three exons of the transcript, a region that has been identified as an imprinting center. Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region but the full-length nature of these transcripts has not been determined. An alternate exon has been identified that substitutes for exon 4 and leads to a truncated, monocistronic transcript. Alternative splicing or deletion caused by a translocation event in the 5' UTR or coding region of this gene leads to Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. The function of this protein is not yet known.

Recommended Dilutions: Western Blot: 1:1000, Immunohistochemistry: 1:50-1:100, Flow Cytometry: 1:10-1:50

Type: Primary
Antigen: SNURF (SNRPN upstream reading frame)
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Rabbit
Isotype: none
Reactivity: Human
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