Anti-INPP5D Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology
PA512463
CAPIPA5-12463EA 2814.74 CAD
CAPIPA5-12463
Anti-INPP5D Rabbit Polyclonal Antibody
This antibody is predicted to react with mouse and rat based on sequence homology. INPP5D is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and it is a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival.

Recommended Dilutions: Western Blot: 1:1000

Type: Primary
Antigen: INPP5D (inositol polyphosphate-5-phosphatase, 145kDa)
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Rabbit
Isotype: none
Reactivity: Human
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