Anti-AKT1 Rabbit Polyclonal Antibody

PA512541 PA512541
CAPIPA5-12541EA 1221.41 CAD
PIPA5-12541 CAPIPA5-12541
Anti-AKT1 Rabbit Polyclonal Antibody
This antibody is predicted to react with bovine, mouse, rat and Xenopus based on sequence homology. AKT1belongs to the protein kinase C superfamily. This kinase is activated bythe Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis.

Recommended Dilutions: Western Blot: 1:1000

Type: Primary
Antigen: AKT1
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse
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