Anti-FGFR Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology
PA512595
CAPIPA5-12595EA 1983.03 CAD
CAPIPA5-12595
Anti-FGFR Rabbit Polyclonal Antibody
This antibody is predicted to react with chicken, rat and zebrafish based on sequence homology. FGFR is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene can lead to Pfeiffer syndrome and Jackson-Weiss syndrome.

Recommended Dilutions: Western Blot: 1:1000, Immunohistochemistry: 1:50-1:100

Type: Primary
Antigen: FGFR
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Rabbit
Isotype: none
Reactivity:
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