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Anti-TNFRSF1A Rabbit Polyclonal Antibody
Anti-TNFRSF1A Rabbit Polyclonal Antibody
Catalog #: CAPIPA5-12709
Supplier:  Thermo Scientific
Anti-TNFRSF1A Rabbit Polyclonal Antibody
Catalog #: CAPIPA5-12709
Supplier:  Thermo Scientific
Price
3 072,55 $
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Unit of Measure Each (100µG)
Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
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Specifications

  • Antibody type:
    Primary
  • Antigen name:
    Tumer Necrosis Factor Receptor 1
  • ChIP:
    Yes
  • Clonality:
    Polyclonal
  • Gel shift:
    Yes
  • Gene ID:
    TNFRSF1A/7132; Tnfrsf1a/21937
  • Host:
    Rabbit
  • Isotype:
    IgG
  • Neutralisation:
    Yes
  • Reactivity:
    Human,
    Mouse
  • Antigen symbol:
    TNFR1
  • Conjugation:
    Unconjugated
  • ELISA:
    Yes
  • Flow cytometry:
    Yes
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • ImmunoPrecipitation:
    Yes
  • Size:
    400 µL
  • Western blot:
    Yes
  • Cross adsorption:
    No
  • Form:
    Liquid
  • Antigen synonyms:
    TNFRSF1A,
    Tumor necrosis factor receptor superfamily member 1A [Precursor],
    TNFR-I,
    p55,
    CD120a antigen,
    TNFAR,
    p60,
    TNF-R1,
    TNFR1,
    TNF-RI
  • Modification:
    phospho-Ser274
  • Storage buffer:
    PBS with 0.09% Sodium azide
  • Molecular weight:
    50.5 kDa
  • Storage temperature:
    Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at –20 °C
  • Concentration:
    Lot-specific
  • Immunogen:
    KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S274 of human TNFR1
  • Tested applications:
    Immunohistochemistry
  • Purification:
    Antigen affinity chromatography
  • Cat. no.:
    CAPIPA5-12709

Specifications

About this item

A member of the TNF-receptor superfamily, this protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease.

Recommended Dilutions: Western Blot: 1:1000, Immunohistochemistry: 1:50-1:100

Type: Primary
Antigen: TNFRSF1A (tumor necrosis factor receptor superfamily, member 1A)
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Rabbit
Isotype: none
Reactivity:

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