Anti-EP300 Rabbit Polyclonal Antibody

PA512735 PA512735
CAPIPA5-12735EA 1221.41 CAD
PIPA5-12735 CAPIPA5-12735
Anti-EP300 Rabbit Polyclonal Antibody
EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CBP (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CBP can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.

Recommended Dilutions: Immunohistochemistry: 1:10-1:50, Dot blot: 1:500

Type: Primary
Antigen: EP300
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human
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