Anti-TSC2 Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology

PA512862
CAPIPA5-12862EA 2800.97 CAD
CAPIPA5-12862
Anti-TSC2 Rabbit Polyclonal Antibody
Antibodies
Mutations in TSC2 lead to tuberous sclerosis complex. The protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking.

Recommended Dilutions: Immunofluorescence: 1:10-1:50, Immunocytochemistry: 1:10-1:50, Dot blot: 1:500

Type: Primary
Antigen: TSC2 (tuberous sclerosis 2)
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Rabbit
Isotype: none
Reactivity: Human
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