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Anti-TSC2 Rabbit Polyclonal Antibody
Anti-TSC2 Rabbit Polyclonal Antibody
Catalog #: CAPIPA5-12862
Supplier:  Thermo Scientific
Anti-TSC2 Rabbit Polyclonal Antibody
Catalog #: CAPIPA5-12862
Supplier:  Thermo Scientific
Price
$3,214.72
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Unit of Measure Each (100µG)
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Specifications

  • Antibody type:
    Primary
  • Antigen name:
    Tuberous sclerosis 2 protein
  • ChIP:
    Yes
  • Clonality:
    Polyclonal
  • Gel shift:
    Yes
  • Host:
    Rabbit
  • Isotype:
    IgG
  • Neutralisation:
    Yes
  • Reactivity:
    Human
  • Antigen symbol:
    TSC2
  • Conjugation:
    Unconjugated
  • ELISA:
    Yes
  • Flow cytometry:
    Yes
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • ImmunoPrecipitation:
    Yes
  • Size:
    400 µL
  • Western blot:
    Yes
  • Cross adsorption:
    No
  • Form:
    Liquid
  • Antigen synonyms:
    TSC4,
    LAM,
    TSC2,
    Tuberous sclerosis 2 protein,
    Tuberin
  • Modification:
    phospho-Ser664
  • Storage buffer:
    PBS with 0.09% Sodium azide
  • Molecular weight:
    200.75 kDa
  • Storage temperature:
    Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at –20 °C
  • Concentration:
    Lot-specific
  • Immunogen:
    KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S664 of human TSC2
  • Tested applications:
    Dot Blot
  • Purification:
    Antigen affinity chromatography
  • Cat. no.:
    CAPIPA5-12862

Specifications

About this item

Mutations in TSC2 lead to tuberous sclerosis complex. The protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking.

Recommended Dilutions: Immunofluorescence: 1:10-1:50, Immunocytochemistry: 1:10-1:50, Dot blot: 1:500

Type: Primary
Antigen: TSC2 (tuberous sclerosis 2)
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Rabbit
Isotype: none
Reactivity: Human

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