Anti-MAPK8 Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology

PA512867
CAPIPA5-12867EA 2286.72 CAD
CAPIPA5-12867
Anti-MAPK8 Rabbit Polyclonal Antibody
Antibodies
This antibody is predicted to react with mouse, rat and Xenopus based on sequence homology. MAPK8 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation.

Recommended Dilutions: Dot blot: 1:500

Type: Primary
Antigen: MAPK8 (mitogen-activated protein kinase 8)
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Rabbit
Isotype: none
Reactivity: Human
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