Anti-MAPK Rabbit Polyclonal Antibody

PA512868 PA512868
CAPIPA5-12868EA 1227.26 CAD
CAPIPA5-12868 PIPA5-12868
Anti-MAPK Rabbit Polyclonal Antibody
This antibody is predicted to react with mouse based on sequence homology. MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.

Recommended Dilutions: Dot blot: 1:500

Type: Primary
Antigen: MAPK
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human
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