Anti-RPTOR Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology
PA512924
CAPIPA5-12924EA 2128.34 CAD
CAPIPA5-12924
Anti-RPTOR Rabbit Polyclonal Antibody
Raptor participates in the FRAP1 pathway and associates in a near stoichiometric ratio with FRAP1 to form a nutrient-sensitive complex (NSC). It plays a pivotal role as a scaffold protein in the FRAP1-signaling pathway and this interaction is essential for the catalyzed phosphorylation of EIF4EBP1. It has a positive role in nutrient-stimulated signaling to the downstream effector RPS6KB1. Under nutrient-deprived conditions, raptor serves as a negative regulator of FRAP1 kinase activity. Regulation of the interaction with FRAP1 is a critical mechanism by which cells coordinate the rate of cell growth and maintenance of cell size with different environmental conditions.

Recommended Dilutions: Dot blot: 1:500

Type: Primary
Antigen: RPTOR (regulatory associated protein of MTOR, complex 1)
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Rabbit
Isotype: none
Reactivity: Human
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