Anti-ANTXR1 Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology

PA513032
CAPIPA5-13032EA 2573.22 CAD
CAPIPA5-13032
Anti-ANTXR1 Rabbit Polyclonal Antibody
Antibodies
This antibody is predicted to react with mouse and rat based on sequence homology. ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.

Recommended Dilutions: Dot blot: 1:500

Type: Primary
Antigen: ANTXR1 (anthrax toxin receptor 1)
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Rabbit
Isotype: none
Reactivity: Human
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