Anti-TERT Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology

PA513048
CAPIPA5-13048EA 2801.79 CAD
CAPIPA5-13048
Anti-TERT Rabbit Polyclonal Antibody
Antibodies
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks.

Recommended Dilutions: Immunofluorescence: 1:10-1:50, Immunocytochemistry: 1:10-1:50, Dot blot: 1:500

Type: Primary
Antigen: TERT (telomerase reverse transcriptase)
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Rabbit
Isotype: none
Reactivity: Human
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