Anti-MMP14 Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology

PA513183
CAPIPA5-13183EA 2801.79 CAD
CAPIPA5-13183
Anti-MMP14 Rabbit Polyclonal Antibody
Antibodies
This antibody is predicted to react with bovine, mouse, porcine and rat based on sequence homology. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP14 seems to specifically activate progelatinase A, and may thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. Expression is significant in stromal cells of colon, breast, and head and neck.

Recommended Dilutions: Western Blot: 1:1000, Immunohistochemistry: 1:50-1:100, Flow Cytometry: 1:10-1:50

Type: Primary
Antigen: MMP14 (matrix metallopeptidase 14 (membrane-inserted))
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Rabbit
Isotype: none
Reactivity: Human
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