Anti-MMP8 Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology
PA513198
CAPIPA5-13198EA 2814.74 CAD
CAPIPA5-13198
Anti-MMP8 Rabbit Polyclonal Antibody
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, MMP8 is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Recommended Dilutions: Western Blot: 1:1000, Immunohistochemistry: 1:50-1:100

Type: Primary
Antigen: MMP8 (matrix metallopeptidase 8 (neutrophil collagenase))
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Rabbit
Isotype: none
Reactivity:
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