Anti-NOTCH3 Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology

PA513203
CAPIPA5-13203EA 2801.79 CAD
CAPIPA5-13203
Anti-NOTCH3 Rabbit Polyclonal Antibody
Antibodies
This antibody is predicted to react with human based on sequence homology. NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

Recommended Dilutions: Western Blot: 1:1000, Immunofluorescence: 1:10-1:50, Immunocytochemistry: 1:10 - 1:50, Immunohistochemistry: 1:50-1:100

Type: Primary
Antigen: NOTCH3 (notch 3)
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Rabbit
Isotype: none
Reactivity: Human
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