Anti-OAS3 Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology
CAPIPA5-13211EA 2561.45 CAD
Anti-OAS3 Rabbit Polyclonal Antibody
OAS3 is an interferon inducible protein that belongs to the 2-5A synthetase family, may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS3 synthesizes preferentially dimeric 2',5'-oligoadenylate molecules. GTP can be an alternative substrate. OAS3 binds double-stranded RNA and polymerizes ATP into PPP(A2'P5'A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. The protein is present at high level in placenta trophoblast.

Recommended Dilutions: Western Blot: 1:1000

Type: Primary
Antigen: OAS3 (2'-5'-oligoadenylate synthetase 3, 100kDa)
Clonality: polyclonal
Conjugation: unconjugated
Host: Rabbit
Isotype: none
Reactivity: Human
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