Anti-HIRA Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology
PA513269
CAPIPA5-13269EA 2444.36 CAD
CAPIPA5-13269
Anti-HIRA Rabbit Polyclonal Antibody
This antibody is predicted to react with chicken, mouse and Xenopus based on sequence homology. HIRA is a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this protein in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. It plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate protein in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.

Recommended Dilutions: Western Blot: 1:1000

Type: Primary
Antigen: HIRA (histone cell cycle regulator)
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Rabbit
Isotype: none
Reactivity: Human
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