Anti-YBX1 Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology

PA513307
CAPIPA5-13307EA 2573.22 CAD
CAPIPA5-13307
Anti-YBX1 Rabbit Polyclonal Antibody
Antibodies
This antibody is predicted to react with bovine, mouse, rat and Xenopus based on sequence homology. YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. This protein binds and stabilizes cytoplasmic mRNA and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. It regulates the transcription of numerous genes and promotes separation of DNA strands that contain mismatches or are modified by cisplatin. It has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro), and it may play a role in DNA repair.

Recommended Dilutions: Western Blot: 1:1000, Immunofluorescence: 1:10-1:50, Immunocytochemistry: 1:10-1:50

Type: Primary
Antigen: YBX1 (Y box binding protein 1)
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Rabbit
Isotype: none
Reactivity: Human
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