Anti-ZBTB7B Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology
CAPIPA5-13382EA 2561.45 CAD
Anti-ZBTB7B Rabbit Polyclonal Antibody
ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.

Recommended Dilutions: Western Blot: 1:1000, Immunohistochemistry: 1:50

Type: Primary
Antigen: ZBTB7B (zinc finger and BTB domain containing 7B)
Clonality: polyclonal
Conjugation: unconjugated
Host: Rabbit
Isotype: none
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