Anti-Alsin Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology

PA513426
CAPIPA5-13426EA 2801.79 CAD
CAPIPA5-13426
Anti-Alsin Rabbit Polyclonal Antibody
Antibodies
This antibody is predicted to react with rat based on sequence homology. ALS2 contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in its gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis.

Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1000

Type: Primary
Antigen: Alsin
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse
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