Anti-F10 Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology
PA513688
CAPIPA5-13688EA 2561.45 CAD
CAPIPA5-13688
Anti-F10 Rabbit Polyclonal Antibody
F10 is the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting.

Recommended Dilutions: Western Blot: 1:1000, Immunohistochemistry: 1:50-1:100, Flow Cytometry: 1:10-1:50

Type: Primary
Antigen: F10 (coagulation factor X)
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Rabbit
Isotype: none
Reactivity: Human
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