Anti-PRKCE Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology

PA513745
CAPIPA5-13745EA 2573.22 CAD
CAPIPA5-13745
Anti-PRKCE Rabbit Polyclonal Antibody
Antibodies
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PKC epsilon is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior.

Recommended Dilutions: Western Blot: 1:1000, Immunohistochemistry: 1:50-1:100

Type: Primary
Antigen: PRKCE (protein kinase C, epsilon)
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Rabbit
Isotype: none
Reactivity: Human
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